12 16.4 Statement relating to Corporate Governance 168 TREND INFORMATION 141 16.5 Operating principals of the Board of Directors 170 12.1Most significant recent trends since the end of the last financial year 142 12.2I nformation on any known trends, uncertainties, 17 EMPLOYEES 171 demands, commitments or events that are reasonably likely to have a material effect 17.1 Human Resources Management 172 on the Company’s prospects 142 17.2 Corporate Social Responsibility 172 17.3 Shareholdings and share warrants or share 13 PROFIT FORECASTS OR ESTIMATES 143 warrants for founders held by Members of the Board of Directors and Senior Management 173 17.4 Employee shareholding plan and long-term incentive plans 173 14 ADMINISTRATIVE, MANAGEMENT AND SUPERVISORY BODIES 17.5 Profit-Sharing Agreements and Incentive Schemes 173 AND SENIOR MANAGEMENT 145 14.1Composition of management 18 and supervisory bodies 146 MAJOR SHAREHOLDERS 175 14.2Conflicts of interest 151 18.1 Allocation of share capital 176 18.2 Shareholders’ voting rights 178 15 18.3 Control structure 178 COMPENSATION AND BENEFITS 153 18.4 Shareholders’ Agreement 179 15.1Compensation and benefits of Senior Executives 154 18.5 Agreements likely to lead to a change of control 179 15.2Directors’ compensation 157 18.6 Lock-up Agreement 179 15.3Share warrants, share warrants for founders, stock options and free shares granted 18.7 Pledges on Company’s shares 179 to Senior Executives and Directors 159 15.4 History of allocation of share warrants, share warrants for founders and stock options 161 19 RELATED PARTY TRANSACTIONS 181 15.5Share warrants, share warrants for founders 19.1 Agreements with the Company’s Major or stock options of the Company granted Shareholders 182 to the Company’s top ten employees 163 19.2 Transactions with Key Management Persons 182 15.6History of allocation of free shares 163 19.3 Statutory Auditor’s Report on regulated 15.7Benefits of Senior Executives 164 Agreements and Commitments 15.8Compliance of total Executive Director for the fiscal year ending December 31, 2017 183 compensation with the recommendations of MiddleNext Code 164 15.9Amount of provisions made or recorded 20 FINANCIAL INFORMATION CONCERNING by the Company for the payment of pensions, THE GROUP’S ASSETS AND LIABILITIES, retirement plans or other benefits 164 FINANCIAL POSITION AND PROFITS AND LOSSES 185 20.1 Historical financial information 186 16 BOARD PRACTICES 165 20.2 Date of latest financial information 214 16.1Terms of office of Members of the corporate 20.3 Historical financial information for the fiscal bodies and management bodies 166 years ending December 31, 2015 and 2016 214 16.2I nformation on Service Contracts between 20.4 Dividend policy 214 members of the administrative and management bodies and the Company 166 20.5 Legal and arbitration proceedings 214 16.3Committees of the Board of Directors 166 20.6 Significant change in financial or trading position 214 GENSIGHT BIOLOGICS – 2017 Registration Document – 7