PROPERTY, PLANT AND EQUIPMENT 8 Information required by Article R.225-105-1 of the French Commercial Code Registration Document Comment Sustainable use of resources Water consumption and water supplies based on local constraints Section 8.2 Consumption of raw materials and steps taken to improve efficiency of use Section 8.2 Energy consumption, steps taken to improve energy efficiency and use of Section 8.2 renewable energy Land use Given the Company’s activities, this information is not relevant. Climate change Greenhouse gas emissions Section 8.2 Adaptation to climate change impacts Given the Company’s Medium and long term targets set on a voluntary basis to reduce greenhouse activities, this information gas emissions and measures taken to this effect is not relevant. Protection of biodiversity Steps taken to preserve or restore biodiversity Given the Company’s activities, this information is not relevant. Social commitment in favour of sustainable development Impact of the Company’s operations on employment and local development Section 8.2 Impact of the Company’s operations neighboring and local populations Section 8.2 Relationships with society’s stakeholders and dialogue terms with them Section 8.2 Partnership and sponsorship activities Section 8.2 Sub-contracting and suppliers Consideration of social and environmental issues in the Company’s purchasing Section 8.2 policy Significance of sub-contracting and consideration, in relationships with Section 8.2 sub-contractors and suppliers, of their social and environmental responsibility Fair business practices Steps taken to ensure consumer health and safety Section 8.2 Fight against corruption Actions taken to prevent corruption Section 8.2 Human Rights promotion and compliance with the provisions of the International Labor Organization Other steps taken to support human rights Section 8.2 GENSIGHT BIOLOGICS – 2017 Registration Document– 107