GenSight Biologics S.A. Corporation (société anonyme)with a share capital of €605,855.58 Registered Office: 74, rue du Faubourg Saint-Antoine 75012 Paris, France 751 164 757 Paris Trade and Companies Register 2017 REGISTRATION DOCUMENT INCLUDING THE ANNUAL FINANCIAL REPORT THE MANAGEMENT REPORT AND THE CORPORATE GOVERNANCE REPORT In accordance with its General Regulations (Règlement Général)and, in particular Article 212-23 thereof, the Autorité des marchés financiers (the “AMF”) registered this Registration Document on April 27, 2018 under number R.18-036. This document may not be used in the context of any securities offering unless completed by a Securities Note in respect of which the AMF has granted a visa. The Registration Document has been prepared by the issuer, and its signatories therefore assume responsibility for its contents. This registration was granted after the AMF had verified that the document is complete and comprehensible and that the information it contains is coherent, in accordance with the provisions of Article L.621-8-1-I of the French Monetary and Financial Code. It does not imply that the AMF has verified the accounting and financial information presented herein. The Registration Document is publicly available on the website of the AMF (www.amf-france.org). Copies of the Registration Document may also be obtained free of charge at GenSight Biologics S.A.’s registered office at 74, rue du Faubourg Saint-Antoine – 75012 Paris, France, as well as on the website of GenSight Biologics S.A., (www.gensight-biologics.com).